Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755815 | 0.85 | EGLN1 (0.47) | SLC22A6LMNATSHRNFKB1PMP22 | |
| SCHEMBL7998260 | 0.82 | MCL1 (0.43) | LMNATSHRNFKB1PMP22FOLH1 | |
| SCHEMBL8010699 | 0.82 | MCL1 (0.43) | LMNATSHRNFKB1PMP22FOLH1 | |
| SCHEMBL9732634 | 0.79 | SLC22A6 (0.50) | SLC22A6LMNATSHRNFKB1PMP22 | |
| SCHEMBL3899647 | 0.76 | — | — | |
| SCHEMBL503328 | 0.76 | SLC22A6 (0.79) | SLC22A6LMNATSHRNFKB1PMP22 | |
| Glutarate SCHEMBL31358954 | 0.76 | SLC22A6 (0.92) | SLC22A6LMNATSHRNFKB1PMP22 | |
| Glutarate SCHEMBL31358952 | 0.76 | SLC22A6 (0.92) | SLC22A6LMNATSHRNFKB1PMP22 | |
| Glutarate SCHEMBL5603986 | 0.76 | SLC22A6 (0.92) | SLC22A6LMNATSHRNFKB1PMP22 | |
| Glutarate SCHEMBL6368693 | 0.76 | SLC22A6 (0.92) | SLC22A6LMNATSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005763-A1 | DIPEPTIDE-ANALOG-BASED METALLOENDOPEPTIDASE INHIBITORS AND METHODS OF USING SAME | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |