Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.45 |
| ▸ | KDM6B | O15054 | 2/20 | 0.45 |
| ▸ | KDM5C | P41229 | 2/20 | 0.45 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESRRB | O95718 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Succinate SCHEMBL28154694 | 0.88 | TSHR (0.77) | TSHRLMNAALDH1A1KMT2AHTT | |
| Dimethyl Succinate SCHEMBL28606769 | 0.88 | TSHR (0.77) | TSHRLMNAALDH1A1KMT2AHTT | |
| Succinic Acid SCHEMBL18063898 | 0.88 | TSHR (0.77) | TSHRLMNAALDH1A1KMT2AHTT | |
| SCHEMBL164072 | 0.88 | — | — | |
| Dimethyl Succinate SCHEMBL20335703 | 0.88 | TSHR (0.77) | TSHRLMNAALDH1A1KMT2AHTT | |
| Dimethyl Succinate SCHEMBL29626086 | 0.88 | TSHR (0.77) | TSHRLMNAALDH1A1KMT2AHTT | |
| SCHEMBL28270066 | 0.88 | TSHR (0.77) | TSHRLMNAALDH1A1KMT2AHTT | |
| SCHEMBL11672392 | 0.85 | TSHR (0.72) | TSHRLMNAALDH1A1KMT2AHTT | |
| SCHEMBL6396564 | 0.85 | TSHR (0.72) | TSHRLMNAALDH1A1KMT2AHTT | |
| Ammonia Solution, Strong SCHEMBL17600636 | 0.85 | TSHR (0.72) | TSHRLMNAALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005763-A1 | DIPEPTIDE-ANALOG-BASED METALLOENDOPEPTIDASE INHIBITORS AND METHODS OF USING SAME | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |