Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755996 | 0.93 | CYP3A4 (0.49) | CYP3A4CYP2C9POLBNPC1ABCB1 | |
| SCHEMBL9756267 | 0.92 | CYP3A4 (0.48) | CYP3A4CYP2C9POLBNPC1ABCB1 | |
| SCHEMBL9756122 | 0.88 | CYP3A4 (0.53) | CYP3A4CYP2C9POLBMEN1KMT2A | |
| SCHEMBL9755906 | 0.88 | POLB (0.61) | CYP3A4CYP2C9POLBMEN1KMT2A | |
| SCHEMBL9755989 | 0.87 | ABCB1 (0.60) | CYP3A4CYP2C9POLBMEN1KMT2A | |
| SCHEMBL9755975 | 0.85 | CYP3A4 (0.49) | CYP3A4CYP2C9POLBHTTNPC1 | |
| SCHEMBL9756336 | 0.84 | CYP3A4 (0.52) | CYP3A4CYP2C9POLBHTTNPC1 | |
| SCHEMBL9756540 | 0.83 | CYP3A4 (0.47) | CYP3A4CYP2C9POLBHTTNPC1 | |
| SCHEMBL9756335 | 0.83 | ABCB1 (0.43) | NPC1ABCB1 | |
| SCHEMBL9756048 | 0.82 | CYP3A4 (0.46) | CYP3A4CYP2C9POLBHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |