Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756356 | 1.00 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2ABCB1CTSD | |
| SCHEMBL9755843 | 1.00 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2ABCB1CTSD | |
| SCHEMBL9755927 | 0.99 | MEN1 (0.48) | KMT2AMEN1SMN1; SMN2ABCB1CTSD | |
| SCHEMBL9756078 | 0.96 | ABCB1 (0.47) | KMT2AMEN1ABCB1CTSDTDP1 | |
| SCHEMBL9755863 | 0.95 | ABCB1 (0.50) | ABCB1CTSDTDP1STAT3 | |
| SCHEMBL9756355 | 0.81 | SMN1; SMN2 (0.53) | KMT2AMEN1SMN1; SMN2ABCB1 | |
| SCHEMBL9755879 | 0.81 | SMN1; SMN2 (0.53) | KMT2AMEN1SMN1; SMN2ABCB1 | |
| SCHEMBL9755842 | 0.81 | SMN1; SMN2 (0.53) | KMT2AMEN1SMN1; SMN2ABCB1 | |
| SCHEMBL8166805 | 0.80 | POLB (0.60) | — | |
| SCHEMBL9755972 | 0.80 | POLB (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |