Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756169 | 1.00 | CYP3A4 (0.52) | CYP3A4CYP2C9RECQLPOLBABCB1 | |
| SCHEMBL9755938 | 1.00 | CYP3A4 (0.52) | CYP3A4CYP2C9RECQLPOLBABCB1 | |
| SCHEMBL9756088 | 0.86 | CYP3A4 (0.53) | CYP3A4CYP2C9RECQLPOLBABCB1 | |
| SCHEMBL9755917 | 0.86 | ABCB1 (0.62) | CYP3A4CYP2C9POLBABCB1HTT | |
| SCHEMBL9755911 | 0.86 | ABCB1 (0.62) | CYP3A4CYP2C9POLBABCB1HTT | |
| SCHEMBL9756031 | 0.86 | ABCB1 (0.62) | CYP3A4CYP2C9POLBABCB1HTT | |
| SCHEMBL9756209 | 0.84 | POLB (0.65) | CYP3A4CYP2C9RECQLPOLBABCB1 | |
| SCHEMBL9756395 | 0.84 | POLB (0.65) | CYP3A4CYP2C9RECQLPOLBABCB1 | |
| SCHEMBL9755912 | 0.84 | POLB (0.65) | CYP3A4CYP2C9RECQLPOLBABCB1 | |
| SCHEMBL9755889 | 0.82 | CYP3A4 (0.58) | CYP3A4CYP2C9RECQLPOLBABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |