Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755920 | 0.93 | NPC1 (0.55) | ABCB1CYP3A4CYP2C9RAB9ANPC1 | |
| SCHEMBL9756228 | 0.92 | ABCB1 (0.54) | ABCB1CYP3A4CYP2C9RAB9ANPC1 | |
| SCHEMBL9755903 | 0.89 | POLB (0.61) | CYP3A4CYP2C9SMN1; SMN2POLBMEN1 | |
| SCHEMBL9756424 | 0.88 | ABCB1 (0.60) | ABCB1CYP3A4CYP2C9SMN1; SMN2POLB | |
| SCHEMBL9755855 | 0.87 | CYP3A4 (0.54) | CYP3A4CYP2C9RAB9ASMN1; SMN2POLB | |
| SCHEMBL9756305 | 0.85 | ABCB1 (0.62) | ABCB1CYP3A4CYP2C9POLBTDP1 | |
| SCHEMBL9756224 | 0.83 | ABCB1 (0.60) | ABCB1CYP3A4CYP2C9TDP1 | |
| SCHEMBL9756451 | 0.82 | ABCB1 (0.51) | ABCB1CYP3A4CYP2C9MEN1KMT2A | |
| SCHEMBL9756402 | 0.82 | ABCB1 (0.69) | ABCB1CYP3A4CYP2C9POLBTDP1 | |
| SCHEMBL9756064 | 0.82 | ABCB1 (0.58) | ABCB1CYP3A4CYP2C9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |