SCHEMBL9756007

SCHEMBL9756007

CC(C)(C)N(NC(=O)c1ccc(Cl)cc1)C(=O)CCCCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TMEM97 Q5BJF2 1/20 0.51
SIGMAR1 Q99720 1/20 0.51
SCN5A Q14524 1/20 0.48
SCN2A Q99250 1/20 0.48
ALOX5 P09917 1/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9756126 0.96 TMEM97 (0.52) TMEM97SIGMAR1SCN5ASCN2APOLB
SCHEMBL9755942 0.95 POLB (0.51) POLB
SCHEMBL9756116 0.94 HPGD (0.50) POLB
SCHEMBL9756115 0.92 POLB (0.51) TMEM97SIGMAR1POLB
SCHEMBL9756021 0.92 POLB (0.57) ALOX5POLB
SCHEMBL9756170 0.88 POLB (0.58) POLB
SCHEMBL9756426 0.84 HPGD (0.49) POLB
SCHEMBL9755968 0.84 POLB (0.54) POLB
SCHEMBL9756453 0.84 ABCB1 (0.54)
SCHEMBL9756123 0.83 HPGD (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0234944-B1 INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1991-04-10 EP disclosed
EP-0232075-B1 INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES ROHM AND HAAS COMPANY (US) 1991-03-13 EP disclosed
EP-0234944-A1 Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines ROHM AND HAAS COMPANY (US) 1987-09-02 EP disclosed