Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756400 | 0.85 | CYP3A4 (0.53) | ABCB1CYP3A4CYP2C9POLBHTT | |
| SCHEMBL9756202 | 0.84 | POLB (0.67) | ABCB1CYP3A4CYP2C9POLBCYP2C19 | |
| SCHEMBL9756259 | 0.84 | ABCB1 (0.61) | ABCB1CYP3A4CYP2C9POLBHPGD | |
| SCHEMBL9714226 | 0.83 | ABCB1 (0.89) | ABCB1CYP3A4CYP2C9POLB | |
| SCHEMBL9756171 | 0.83 | ABCB1 (0.70) | ABCB1CYP3A4CYP2C9POLBHPGD | |
| SCHEMBL9756057 | 0.82 | ABCB1 (0.58) | ABCB1CYP3A4CYP2C9POLBHPGD | |
| SCHEMBL9755880 | 0.82 | ABCB1 (0.58) | ABCB1CYP3A4CYP2C9POLBHPGD | |
| SCHEMBL8173866 | 0.81 | ABCB1 (0.57) | ABCB1CYP3A4CYP2C9POLBCYP2C19 | |
| SCHEMBL9507281 | 0.81 | CYP3A4 (0.83) | ABCB1CYP3A4CYP2C9POLB | |
| SCHEMBL10722074 | 0.81 | ABCB1 (0.89) | ABCB1CYP3A4CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |