SCHEMBL9756085

SCHEMBL9756085

CC(C)(C)N(NC(=O)c1ccc(Cl)cc1)C(=O)C1CC1

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.48
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8179772 0.96 POLB (0.45) POLBHPGDSMN1; SMN2
SCHEMBL9756107 0.96 KMT2A (0.45) POLB
SCHEMBL9755864 0.95 MEN1 (0.47) POLBHPGDSMN1; SMN2
SCHEMBL9755858 0.95 MEN1 (0.47) POLBHPGDSMN1; SMN2
SCHEMBL9756132 0.95 MEN1 (0.47) POLBHPGDSMN1; SMN2
SCHEMBL9756040 0.85 POLB (0.67) POLB
SCHEMBL9756137 0.81 POLB (0.53) POLBHPGDSMN1; SMN2
SCHEMBL9714227 0.81 POLB (0.71) POLBHPGDSMN1; SMN2
SCHEMBL9755965 0.81 POLB (0.61) POLB
SCHEMBL9756163 0.81 POLB (0.61) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0234944-B1 INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1991-04-10 EP disclosed
EP-0232075-B1 INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES ROHM AND HAAS COMPANY (US) 1991-03-13 EP disclosed
EP-0234944-A1 Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines ROHM AND HAAS COMPANY (US) 1987-09-02 EP disclosed