Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718620 | 0.87 | ABCB1 (0.59) | ABCB1 | |
| SCHEMBL9756312 | 0.83 | ABCB1 (0.46) | ABCB1ESR1ESR2CYP3A4CYP2C9 | |
| SCHEMBL10748923 | 0.82 | POLB (0.67) | CYP3A4CYP2C9 | |
| SCHEMBL9756157 | 0.82 | ABCB1 (0.45) | ABCB1ESR1ESR2CYP3A4CYP2C9 | |
| SCHEMBL10719341 | 0.81 | ABCB1 (0.56) | ABCB1 | |
| SCHEMBL9755984 | 0.79 | ABCB1 (0.45) | ABCB1 | |
| SCHEMBL9815897 | 0.79 | POLB (0.51) | ABCB1CYP3A4CYP2C9 | |
| SCHEMBL10719141 | 0.79 | ABCB1 (0.57) | ABCB1 | |
| SCHEMBL7701546 | 0.78 | ABCB1 (0.71) | ABCB1 | |
| SCHEMBL9651219 | 0.78 | ATM (0.52) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |