Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755923 | 0.97 | ABCB1 (0.58) | ABCB1NPC1RAB9ACYP3A4CYP2C9 | |
| SCHEMBL9755989 | 0.92 | ABCB1 (0.60) | ABCB1NPC1RAB9ACYP3A4CYP2C9 | |
| SCHEMBL9756453 | 0.90 | ABCB1 (0.54) | ABCB1ALDH1A1 | |
| SCHEMBL9756021 | 0.90 | POLB (0.57) | CYP3A4CYP2C9POLBALOX5 | |
| SCHEMBL9756267 | 0.88 | CYP3A4 (0.48) | ABCB1NPC1CYP3A4CYP2C9POLB | |
| SCHEMBL9756068 | 0.86 | ABCB1 (0.62) | ABCB1CYP3A4CYP2C9 | |
| SCHEMBL9756170 | 0.86 | POLB (0.58) | NPC1RAB9ACYP3A4CYP2C9POLB | |
| SCHEMBL9755873 | 0.85 | ABCB1 (0.60) | ABCB1CYP3A4CYP2C9 | |
| SCHEMBL9756263 | 0.85 | ABCB1 (0.60) | ABCB1CYP3A4CYP2C9 | |
| SCHEMBL9756138 | 0.85 | ABCB1 (0.60) | ABCB1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |