Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756027 | 1.00 | CYP3A4 (0.48) | CYP3A4CYP2C9HTTCYP2C19POLB | |
| SCHEMBL9756328 | 1.00 | CYP3A4 (0.48) | CYP3A4CYP2C9HTTCYP2C19POLB | |
| SCHEMBL9756209 | 0.85 | POLB (0.65) | CYP3A4CYP2C9HTTCYP2C19POLB | |
| SCHEMBL9755912 | 0.85 | POLB (0.65) | CYP3A4CYP2C9HTTCYP2C19POLB | |
| SCHEMBL9756395 | 0.85 | POLB (0.65) | CYP3A4CYP2C9HTTCYP2C19POLB | |
| SCHEMBL9756023 | 0.84 | CYP3A4 (0.49) | CYP3A4CYP2C9HTTCYP2C19POLB | |
| SCHEMBL9756135 | 0.80 | CYP3A4 (0.53) | CYP3A4CYP2C9HTTCYP2C19POLB | |
| SCHEMBL9714227 | 0.80 | POLB (0.71) | CYP3A4CYP2C9POLBSMN1; SMN2HPGD | |
| SCHEMBL9756327 | 0.77 | POLB (0.47) | CYP3A4CYP2C9POLBSMN1; SMN2HPGD | |
| SCHEMBL9756029 | 0.77 | POLB (0.47) | CYP3A4CYP2C9POLBSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |