Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377675 | 0.94 | CDK1 (0.46) | CDK1GAAMAPTNPSR1RAD52 | |
| SCHEMBL11384234 | 0.90 | CDK1 (0.41) | CDK1GAAMAPTNPSR1 | |
| SCHEMBL6535353 | 0.90 | CDK1 (0.43) | CDK1GAAMAPTALDH1A1KDM4E | |
| SCHEMBL11411747 | 0.89 | MAPT (0.53) | CDK1MAPTALDH1A1KDM4ENPC1 | |
| Iodosulfuron SCHEMBL7638003 | 0.89 | CDK1 (0.42) | CDK1GAAMAPTALDH1A1KDM4E | |
| Iodosulfuron SCHEMBL119814 | 0.89 | CDK1 (0.42) | CDK1GAAMAPTALDH1A1KDM4E | |
| SCHEMBL9248880 | 0.89 | CDK1 (0.42) | CDK1GAAMAPTALDH1A1KDM4E | |
| Iodosulfuron SCHEMBL6061256 | 0.88 | CDK1 (0.42) | CDK1GAAMAPTALDH1A1KDM4E | |
| Iodosulfuron SCHEMBL21582014 | 0.88 | CDK1 (0.42) | CDK1GAAMAPTALDH1A1KDM4E | |
| Iodosulfuron SCHEMBL16670263 | 0.88 | CDK1 (0.42) | CDK1GAAMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991004967-A1 | COMPOUNDS USEFUL FOR MEASURING LOW LEVELS OF SULFONYLUREAS BY IMMUNOASSAY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-18 | — | — | WO | disclosed |
| US-4302241-A | N-(PYRIMIDIN-2-YL-AMINOCARBONYL) ARYL SULFONAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-11-24 | — | — | US | disclosed |