Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756357 | 1.00 | HPGD (0.48) | HPGDSMN1; SMN2POLBCYP3A4CYP2C9 | |
| SCHEMBL9756363 | 1.00 | HPGD (0.48) | HPGDSMN1; SMN2POLBCYP3A4CYP2C9 | |
| SCHEMBL9756175 | 0.99 | HPGD (0.49) | HPGDSMN1; SMN2POLBCYP3A4CYP2C9 | |
| SCHEMBL9756364 | 0.91 | HPGD (0.48) | HPGDSMN1; SMN2POLBNPC1ALDH1A1 | |
| SCHEMBL9756394 | 0.91 | HPGD (0.48) | HPGDSMN1; SMN2POLBNPC1ALDH1A1 | |
| SCHEMBL9756359 | 0.91 | HPGD (0.48) | HPGDSMN1; SMN2POLBNPC1ALDH1A1 | |
| SCHEMBL9756181 | 0.89 | HPGD (0.49) | HPGDSMN1; SMN2POLBNPC1ALDH1A1 | |
| SCHEMBL9755887 | 0.89 | POLB (0.51) | HPGDSMN1; SMN2POLBCYP3A4CYP2C9 | |
| SCHEMBL9756452 | 0.88 | POLB (0.62) | HPGDSMN1; SMN2POLBCYP3A4CYP2C9 | |
| SCHEMBL9756449 | 0.88 | POLB (0.62) | HPGDSMN1; SMN2POLBCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |