Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755998 | 0.99 | ABCB1 (0.55) | ABCB1CYP3A4CYP2C9TAS1R3TAS1R1 | |
| SCHEMBL9756065 | 0.97 | ABCB1 (0.57) | ABCB1CYP3A4CYP2C9TAS1R3TAS1R1 | |
| SCHEMBL9756104 | 0.92 | ABCB1 (0.59) | ABCB1CYP3A4CYP2C9TAS1R3TAS1R1 | |
| SCHEMBL9756321 | 0.88 | CYP3A4 (0.42) | ABCB1CYP3A4CYP2C9 | |
| SCHEMBL9756060 | 0.88 | ABCB1 (0.62) | ABCB1CYP3A4CYP2C9TAS1R3TAS1R1 | |
| SCHEMBL9755955 | 0.88 | POLB (0.53) | CYP3A4CYP2C9 | |
| SCHEMBL9755924 | 0.87 | CYP3A4 (0.41) | ABCB1CYP3A4CYP2C9 | |
| SCHEMBL9756458 | 0.86 | POLB (0.52) | CYP3A4CYP2C9 | |
| SCHEMBL9756379 | 0.85 | CYP3A4 (0.43) | ABCB1CYP3A4CYP2C9 | |
| SCHEMBL9755981 | 0.84 | POLB (0.55) | CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |