Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756327 | 1.00 | POLB (0.47) | POLBHPGDSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9756029 | 1.00 | POLB (0.47) | POLBHPGDSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9756396 | 0.85 | POLB (0.65) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9755915 | 0.85 | POLB (0.65) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9756483 | 0.85 | POLB (0.65) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9756026 | 0.84 | POLB (0.48) | POLBHPGDSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9756137 | 0.80 | POLB (0.53) | POLBHPGDSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9714227 | 0.80 | POLB (0.71) | POLBHPGDSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL9756222 | 0.78 | HPGD (0.56) | POLBHPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL9756328 | 0.77 | CYP3A4 (0.48) | POLBHPGDSMN1; SMN2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |