Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755990 | 0.99 | HPGD (0.44) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL9755960 | 0.95 | HPGD (0.45) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL9756101 | 0.91 | HPGD (0.47) | HPGDSMN1; SMN2ABCB1 | |
| SCHEMBL9756458 | 0.88 | POLB (0.52) | — | |
| SCHEMBL9755955 | 0.87 | POLB (0.53) | — | |
| SCHEMBL9756435 | 0.86 | HPGD (0.49) | HPGDSMN1; SMN2ABCB1 | |
| SCHEMBL9755981 | 0.83 | POLB (0.55) | — | |
| SCHEMBL9756439 | 0.82 | HPGD (0.43) | HPGDSMN1; SMN2 | |
| SCHEMBL9755998 | 0.81 | ABCB1 (0.55) | ABCB1 | |
| SCHEMBL9755924 | 0.81 | CYP3A4 (0.41) | SMN1; SMN2HDAC1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |