Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174421 | 0.89 | POLB (0.63) | POLBCYP3A4CYP2C9SMN1; SMN2RECQL | |
| SCHEMBL9756440 | 0.89 | POLB (0.70) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9756297 | 0.88 | POLB (0.74) | POLBCYP3A4CYP2C9SMN1; SMN2RECQL | |
| SCHEMBL9756445 | 0.88 | POLB (0.62) | POLBCYP3A4CYP2C9SMN1; SMN2RECQL | |
| SCHEMBL9756449 | 0.88 | POLB (0.62) | POLBCYP3A4CYP2C9SMN1; SMN2RECQL | |
| SCHEMBL9756452 | 0.88 | POLB (0.62) | POLBCYP3A4CYP2C9SMN1; SMN2RECQL | |
| SCHEMBL9755887 | 0.86 | POLB (0.51) | POLBCYP3A4CYP2C9SMN1; SMN2ABCB1 | |
| SCHEMBL9755944 | 0.85 | ABCB1 (0.67) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9756373 | 0.84 | CYP3A4 (0.56) | POLBCYP3A4CYP2C9RECQLABCB1 | |
| Rh-5849 SCHEMBL1538531 | 0.83 | POLB (1.00) | POLBCYP3A4CYP2C9SMN1; SMN2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |