Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 10/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | RHOC | P08134 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | CCKAR | P32238 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10650833 | 0.92 | HMGCR (0.46) | HMGCRABCB11SLCO1B1HDAC1HDAC2 | |
| SCHEMBL9773648 | 0.86 | HMGCR (0.42) | HMGCRABCB11SLCO1B1HDAC1HDAC2 | |
| SCHEMBL9773646 | 0.86 | HMGCR (0.42) | HMGCRABCB11SLCO1B1HDAC1HDAC2 | |
| SCHEMBL9773769 | 0.85 | HMGCR (0.41) | HMGCRABCB11SLCO1B1HDAC1HDAC2 | |
| SCHEMBL9756757 | 0.84 | HMGCR (0.56) | HMGCRTBXA2RADRA1A | |
| SCHEMBL9665214 | 0.81 | HMGCR (0.42) | HMGCRABCB11CYP2C9SIRT6ABCC3 | |
| SCHEMBL9665217 | 0.81 | HMGCR (0.42) | HMGCRABCB11CYP2C9SIRT6ABCC3 | |
| SCHEMBL9662629 | 0.81 | HMGCR (0.53) | HMGCRABCB11CYP2C9SIRT6ABCC3 | |
| SCHEMBL9662639 | 0.81 | HMGCR (0.53) | HMGCRABCB11CYP2C9SIRT6ABCC3 | |
| SCHEMBL9773771 | 0.81 | HMGCR (0.40) | HMGCRABCB11SLCO1B1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992462-A | Inhibitor of HMG-CoA reductase | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |