Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11494516 | 0.97 | FFAR3 (0.39) | TSHRCYP2C19FFAR3LCKFYN | |
| Acetic Acid SCHEMBL23160915 | 0.97 | FFAR3 (0.39) | TSHRCYP2C19FFAR3LCKFYN | |
| Acetic Acid SCHEMBL19704450 | 0.97 | FFAR3 (0.39) | TSHRCYP2C19FFAR3LCKFYN | |
| Acetic Acid SCHEMBL457661 | 0.97 | FFAR3 (0.39) | TSHRCYP2C19FFAR3LCKFYN | |
| Acetic Acid SCHEMBL20476458 | 0.97 | FFAR3 (0.39) | TSHRCYP2C19FFAR3LCKFYN | |
| Acetic Acid SCHEMBL5873296 | 0.95 | TSHR (0.37) | TSHRCYP2C19FFAR3LCKFYN | |
| Acetic Acid SCHEMBL9615701 | 0.95 | TSHR (0.37) | TSHRCYP2C19FFAR3LCKFYN | |
| Acetic Acid SCHEMBL29139339 | 0.95 | TSHR (0.37) | TSHRCYP2C19FFAR3LCKFYN | |
| Acetic Acid SCHEMBL22126962 | 0.95 | TSHR (0.37) | TSHRCYP2C19FFAR3LCKFYN | |
| Acetic Acid SCHEMBL9795090 | 0.95 | TSHR (0.37) | TSHRCYP2C19FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064561-A | Alkaline hydroxide, protease | DIVERSEY CORPORATION (CA) | 1991-11-12 | — | — | US | disclosed |