Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756924 | 1.00 | DAO (0.47) | DAOHCAR2HDAC3HDAC4HDAC1 | |
| SCHEMBL4063254 | 0.77 | DAO (0.47) | DAOHCAR2HDAC3HDAC4HDAC1 | |
| SCHEMBL390358 | 0.77 | AKR1C3 (0.47) | HCAR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4063251 | 0.77 | DAO (0.47) | DAOHCAR2HDAC3HDAC4HDAC1 | |
| SCHEMBL390357 | 0.77 | AKR1C3 (0.47) | HCAR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9756825 | 0.77 | DAO (0.51) | DAOHCAR2HDAC3HDAC4HDAC1 | |
| SCHEMBL9756823 | 0.77 | DAO (0.51) | DAOHCAR2HDAC3HDAC4HDAC1 | |
| SCHEMBL8746677 | 0.71 | HCAR2 (0.64) | HCAR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8746675 | 0.71 | HCAR2 (0.64) | HCAR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4841041 | 0.71 | KDM4E (0.53) | HCAR2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | disclosed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | disclosed |