Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GSK3B | P49841 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 3/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757027 | 1.00 | KDM4E (0.58) | KDM4EALDH1A1PKMPTGER1PTGER4 | |
| SCHEMBL3095019 | 0.89 | GSK3B (0.51) | KDM4EALDH1A1PKMLMNAGSK3B | |
| SCHEMBL3095033 | 0.89 | GSK3B (0.51) | KDM4EALDH1A1PKMLMNAGSK3B | |
| SCHEMBL15239271 | 0.84 | GSK3B (0.48) | KDM4EALDH1A1PKMLMNAGSK3B | |
| SCHEMBL15239275 | 0.84 | GSK3B (0.48) | KDM4EALDH1A1PKMLMNAGSK3B | |
| SCHEMBL3688515 | 0.84 | CA12 (0.55) | KDM4ELMNAGSK3BBACE1RAB9A | |
| SCHEMBL3688513 | 0.84 | CA12 (0.55) | KDM4ELMNAGSK3BBACE1RAB9A | |
| SCHEMBL3179345 | 0.81 | SRD5A2 (0.56) | KDM4EALDH1A1PKMLMNAP4HTM | |
| SCHEMBL3179354 | 0.81 | SRD5A2 (0.56) | KDM4EALDH1A1PKMLMNAP4HTM | |
| SCHEMBL15177143 | 0.80 | AKT1 (0.48) | PKMGSK3BBACE1RAB9AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | disclosed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | disclosed |