Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22444498 | 0.82 | TSHR (0.50) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL22444530 | 0.81 | TSHR (0.48) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL27024550 | 0.80 | TSHR (0.61) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL28656685 | 0.79 | TSHR (0.47) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL2150976 | 0.78 | TSHR (0.59) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL1838475 | 0.78 | TSHR (0.46) | TSHRGABRA1GABRB2POLBBCHE | |
| SCHEMBL28638989 | 0.77 | TSHR (0.53) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL25271814 | 0.77 | TSHR (0.44) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL9200434 | 0.77 | TSHR (0.44) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL22444462 | 0.77 | TSHR (0.57) | TSHRGABRA1GABRB2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |