Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757009 | 0.93 | CYSLTR1 (0.51) | PDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL9757104 | 0.83 | PDE10A (0.49) | PDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL7101389 | 0.82 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2 | |
| SCHEMBL7715802 | 0.82 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2 | |
| SCHEMBL7717062 | 0.82 | CYSLTR2 (0.59) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757192 | 0.80 | PDE10A (0.51) | PDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL7005427 | 0.79 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2 | |
| SCHEMBL7710931 | 0.79 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2 | |
| SCHEMBL6089355 | 0.78 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2 | |
| SCHEMBL7715810 | 0.78 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |