Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.61 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 16/20 | 0.55 |
| ▸ | TOP2A | P11388 | 2/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757291 | 0.93 | CACNA1F (0.61) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| Hydrochloric Acid SCHEMBL9757379 | 0.92 | CACNA1F (0.60) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9757381 | 0.89 | CACNA1F (0.56) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9757257 | 0.89 | CACNA1F (0.65) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9757244 | 0.89 | CACNA1F (0.65) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9757155 | 0.88 | CACNA1F (0.62) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9757314 | 0.88 | CACNA1F (0.62) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9757458 | 0.87 | CACNA1F (0.69) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9757365 | 0.87 | CACNA1F (0.61) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9757089 | 0.84 | TOP2A (0.54) | POLBKCNH2GSK3BTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |