Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757221 | 0.93 | CYSLTR1 (0.49) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9757105 | 0.93 | GPBAR1 (0.45) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9757125 | 0.86 | CYSLTR1 (0.51) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9757283 | 0.86 | CYSLTR1 (0.38) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9757016 | 0.85 | CYSLTR1 (0.52) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9034209 | 0.85 | CYSLTR1 (0.55) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9034068 | 0.84 | CYSLTR1 (0.56) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9757219 | 0.84 | CYSLTR1 (0.52) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9757276 | 0.83 | CYSLTR2 (0.49) | CYSLTR1CYSLTR2 | |
| SCHEMBL9756983 | 0.83 | CYSLTR2 (0.49) | CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | claimed |
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |