Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.55 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 7/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.54 |
| ▸ | GSK3B | P49841 | 6/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757244 | 0.91 | CACNA1F (0.65) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL9757344 | 0.90 | MEN1 (0.69) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL9757274 | 0.85 | TOP2A (0.57) | KCNH2POLBTOP2ATOP2BKDM4E | |
| SCHEMBL9757257 | 0.83 | CACNA1F (0.65) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL9757290 | 0.82 | MEN1 (0.62) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL9757471 | 0.82 | MEN1 (0.59) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL9757314 | 0.82 | CACNA1F (0.62) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL9757155 | 0.82 | CACNA1F (0.62) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL9757365 | 0.81 | CACNA1F (0.61) | MEN1KMT2AKCNH2CACNA1FPOLB | |
| SCHEMBL6712892 | 0.81 | MEN1 (0.71) | MEN1KMT2AKCNH2CACNA1FPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |