Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757301 | 0.92 | GSK3B (0.49) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9757363 | 0.91 | GSK3B (0.48) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9757433 | 0.91 | GSK3B (0.48) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9757432 | 0.90 | GSK3B (0.56) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9757482 | 0.90 | GSK3B (0.48) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9757487 | 0.86 | CACNA1F (0.62) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL10689688 | 0.82 | GSK3B (0.53) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9757491 | 0.80 | CACNA1F (0.59) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9757214 | 0.79 | CACNA1F (0.62) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8093551 | 0.79 | TOP2A (0.53) | GSK3BPOLBKCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |