Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA4 | P22748 | 4/20 | 0.43 |
| ▸ | CA6 | P23280 | 4/20 | 0.43 |
| ▸ | CA5A | P35218 | 4/20 | 0.43 |
| ▸ | CA7 | P43166 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA3 | P07451 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | F13A1 | P00488 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22043806 | 0.89 | — | — | |
| SCHEMBL11653609 | 0.86 | — | — | |
| SCHEMBL11657008 | 0.86 | — | — | |
| SCHEMBL8760003 | 0.86 | — | — | |
| SCHEMBL11650970 | 0.86 | — | — | |
| SCHEMBL11654302 | 0.86 | — | — | |
| SCHEMBL27345895 | 0.85 | TLR8 (0.35) | CA12CA2CA4CA6CA5A | |
| SCHEMBL11745151 | 0.77 | — | — | |
| SCHEMBL3294242 | 0.74 | EPHX1 (0.48) | CA2CA1TSHRCASP2 | |
| SCHEMBL5252546 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992200-A | Of silver and gold as complexes of a guanidine compoumd | HENKEL CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4895597-A | ION EXCHANGE WITH GUANIDINE FUNCTIONALITY | HENKEL CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |
| US-4814007-A | SOLVENT EXTRACTION, GUANIDINE COMPOUND | HENKEL CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |