Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9758268 | 1.00 | CYP1A2 (0.34) | CYP1A2TLR4LMNAMAPK1HTT | |
| SCHEMBL9758257 | 1.00 | CYP1A2 (0.34) | CYP1A2TLR4LMNAMAPK1HTT | |
| SCHEMBL9758970 | 0.95 | CYP1A2 (0.33) | CYP1A2TLR4 | |
| SCHEMBL9758976 | 0.95 | CYP1A2 (0.33) | CYP1A2TLR4 | |
| SCHEMBL9758965 | 0.95 | CYP1A2 (0.33) | CYP1A2TLR4 | |
| SCHEMBL9758070 | 0.93 | CYP1A2 (0.32) | CYP1A2TLR4 | |
| SCHEMBL9758076 | 0.93 | CYP1A2 (0.32) | CYP1A2TLR4 | |
| SCHEMBL9758079 | 0.93 | CYP1A2 (0.32) | CYP1A2TLR4 | |
| SCHEMBL9758939 | 0.92 | CYP1A2 (0.37) | CYP1A2LMNAMAPK1HTT | |
| SCHEMBL9758944 | 0.92 | CYP1A2 (0.37) | CYP1A2LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985583-A | Liquid Crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0154849-A2 | Cyclohexane derivatives | MERCK PATENT GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |