SCHEMBL9758909

SCHEMBL9758909

CCCCC1CCC(CCc2ccc(C3CCC(C)(CCC)CC3)cc2)CC1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 13/20 0.44
SPHK2 Q9NRA0 7/20 0.38
CYP2C9 P11712 1/20 0.36
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9758903 1.00 SPHK1 (0.44) SPHK1SPHK2CYP2C9ALDH1A1LMNA
SCHEMBL9757739 0.96 SPHK1 (0.46) SPHK1SPHK2CYP2C9ALDH1A1LMNA
SCHEMBL9757749 0.96 SPHK1 (0.46) SPHK1SPHK2CYP2C9ALDH1A1LMNA
SCHEMBL9757882 0.95 SPHK1 (0.48) SPHK1SPHK2CYP2C9
SCHEMBL9757888 0.95 SPHK1 (0.48) SPHK1SPHK2CYP2C9
SCHEMBL9759089 0.95 SPHK1 (0.44) SPHK1SPHK2CYP2C9ALDH1A1LMNA
SCHEMBL9759093 0.95 SPHK1 (0.44) SPHK1SPHK2CYP2C9ALDH1A1LMNA
SCHEMBL9758627 0.94 SPHK1 (0.46) SPHK1SPHK2CYP2C9ALDH1A1LMNA
SCHEMBL9758636 0.94 SPHK1 (0.46) SPHK1SPHK2CYP2C9ALDH1A1LMNA
SCHEMBL9759745 0.93 SPHK1 (0.48) SPHK1SPHK2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4985583-A Liquid Crystals MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-01-15 US disclosed
EP-0154849-B1 CYCLOHEXANE DERIVATIVES MERCK PATENT GmbH (DE) 1989-01-25 EP disclosed
EP-0154849-A2 Cyclohexane derivatives MERCK PATENT GmbH (DE) 1985-09-18 EP disclosed