Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759147 | 1.00 | SPHK1 (0.52) | SPHK1SPHK2ESR2 | |
| SCHEMBL9758163 | 0.96 | SPHK1 (0.49) | SPHK1SPHK2ESR2 | |
| SCHEMBL9758237 | 0.95 | SPHK1 (0.50) | SPHK1SPHK2ESR2 | |
| SCHEMBL9758241 | 0.95 | SPHK1 (0.50) | SPHK1SPHK2ESR2 | |
| SCHEMBL9759580 | 0.95 | SPHK1 (0.51) | SPHK1SPHK2 | |
| SCHEMBL9759205 | 0.94 | SPHK1 (0.56) | SPHK1SPHK2ESR2 | |
| SCHEMBL9759166 | 0.94 | SPHK1 (0.59) | SPHK1SPHK2 | |
| SCHEMBL9759172 | 0.94 | SPHK1 (0.59) | SPHK1SPHK2 | |
| SCHEMBL9759197 | 0.94 | SPHK1 (0.56) | SPHK1SPHK2ESR2 | |
| SCHEMBL9758924 | 0.93 | SPHK1 (0.62) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985583-A | Liquid Crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0154849-A2 | Cyclohexane derivatives | MERCK PATENT GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |