Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 10/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759224 | 1.00 | SPHK1 (0.38) | SPHK1GRIA1GRIA2GRIA3TSHR | |
| SCHEMBL11002854 | 0.99 | SPHK1 (0.40) | SPHK1GRIA1GRIA2GRIA3TSHR | |
| SCHEMBL10997144 | 0.99 | SPHK1 (0.40) | SPHK1GRIA1GRIA2GRIA3TSHR | |
| SCHEMBL11002852 | 0.99 | SPHK1 (0.40) | SPHK1GRIA1GRIA2GRIA3TSHR | |
| SCHEMBL10997141 | 0.99 | SPHK1 (0.40) | SPHK1GRIA1GRIA2GRIA3TSHR | |
| SCHEMBL9649306 | 0.92 | TSHR (0.39) | SPHK1GRIA1GRIA2GRIA3TSHR | |
| SCHEMBL9649297 | 0.92 | TSHR (0.39) | SPHK1GRIA1GRIA2GRIA3TSHR | |
| SCHEMBL9648242 | 0.91 | TSHR (0.41) | SPHK1GRIA1GRIA2GRIA3TSHR | |
| SCHEMBL9648517 | 0.91 | TSHR (0.41) | SPHK1GRIA1GRIA2GRIA3TSHR | |
| SCHEMBL9648248 | 0.91 | TSHR (0.41) | SPHK1GRIA1GRIA2GRIA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985583-A | Liquid Crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0154849-A2 | Cyclohexane derivatives | MERCK PATENT GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |