Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.58 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757895 | 0.99 | SPHK1 (0.56) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL9758355 | 0.96 | SPHK1 (0.62) | SPHK1SPHK2HSD17B10ALDH1A1 | |
| SCHEMBL9758352 | 0.96 | SPHK1 (0.62) | SPHK1SPHK2HSD17B10ALDH1A1 | |
| SCHEMBL9759256 | 0.95 | SPHK1 (0.58) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL9759158 | 0.95 | SPHK1 (0.58) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL9759747 | 0.95 | SPHK1 (0.58) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL9757871 | 0.95 | SPHK1 (0.58) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL9758638 | 0.95 | SPHK1 (0.50) | SPHK1SPHK2RARB | |
| SCHEMBL9758496 | 0.95 | SPHK1 (0.59) | SPHK1SPHK2HSD17B10ALDH1A1 | |
| SCHEMBL9758505 | 0.95 | SPHK1 (0.59) | SPHK1SPHK2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985583-A | Liquid Crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0154849-A2 | Cyclohexane derivatives | MERCK PATENT GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |