Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | PPOX | P50336 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759562 | 0.93 | MEN1 (0.57) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL9759345 | 0.89 | MEN1 (0.51) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL9758975 | 0.89 | MEN1 (0.55) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11017180 | 0.88 | MEN1 (0.61) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL9759130 | 0.88 | MEN1 (0.58) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10782083 | 0.87 | MEN1 (0.55) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10454657 | 0.85 | MEN1 (0.61) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10787740 | 0.84 | MEN1 (0.55) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10781844 | 0.84 | KMT2A (0.57) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10781895 | 0.84 | MEN1 (0.55) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028732-A | Herbicidally active amino diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1991-07-02 | — | — | US | disclosed |
| EP-0130041-B1 | NOVEL HERBICIDAL SUBSTITUTED PYRIDYL PHENYL AND DIPHENYL ETHERS, HERBICIDAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR THE PREPARATION THEREOF AND THE USE THEREOF FOR COMBATING WEEDS | ROHM AND HAAS COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |