Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443918 | 0.92 | CYP3A4 (0.41) | MAPTGAANR4A1APPPPARG | |
| SCHEMBL9703612 | 0.91 | MAPT (0.52) | MAPTGAAAPPPPARGALDH1A1 | |
| SCHEMBL12585351 | 0.85 | MAPT (0.39) | MAPTGAANR4A1APPPPARG | |
| SCHEMBL14682408 | 0.84 | MAPT (0.46) | MAPTGAAPPARGALDH1A1MAOA | |
| SCHEMBL5685420 | 0.84 | MAPT (0.55) | MAPTGAAPPARGALDH1A1MAPK1 | |
| SCHEMBL3185135 | 0.84 | GAA (0.66) | MAPTGAAAPPPPARGALDH1A1 | |
| SCHEMBL14682418 | 0.83 | GAA (0.46) | MAPTGAAPPARGALDH1A1 | |
| SCHEMBL6831255 | 0.83 | MAPT (0.44) | MAPTGAAAPPPPARGALDH1A1 | |
| SCHEMBL14682414 | 0.83 | MAPT (0.46) | MAPTGAAPPARGALDH1A1MAPK1 | |
| SCHEMBL1892055 | 0.83 | MAPT (0.44) | MAPTGAAPPARGALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997860-A | Amino-substituted silanediol or silanetriol | TOSHIBA SILICONE CO., LTD. (JP) | 1991-03-05 | — | — | US | disclosed |