Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389940 | 0.91 | SLC2A1 (0.53) | ADRB2SLC2A1KDM4ETP53CYP1A2 | |
| SCHEMBL9741835 | 0.84 | SLC2A1 (0.57) | ADRB2SLC2A1KDM4ETP53CYP1A2 | |
| Picumeterol SCHEMBL156907 | 0.84 | SLC2A1 (0.57) | ADRB2SLC2A1KDM4ETP53CYP1A2 | |
| SCHEMBL10418436 | 0.84 | SLC2A1 (0.59) | ADRB2SLC2A1KDM4ETP53CYP1A2 | |
| SCHEMBL10416913 | 0.84 | SLC2A1 (0.57) | ADRB2SLC2A1KDM4ETP53CYP1A2 | |
| Picumeterol SCHEMBL83175 | 0.84 | SLC2A1 (0.57) | ADRB2SLC2A1KDM4ETP53CYP1A2 | |
| SCHEMBL10416519 | 0.84 | SLC2A1 (0.59) | ADRB2SLC2A1KDM4ETP53CYP1A2 | |
| Picumeterol SCHEMBL9857897 | 0.84 | SLC2A1 (0.57) | ADRB2SLC2A1KDM4ETP53CYP1A2 | |
| Picumeterol SCHEMBL29414334 | 0.84 | SLC2A1 (0.57) | ADRB2SLC2A1KDM4ETP53CYP1A2 | |
| SCHEMBL10391329 | 0.83 | SLC2A1 (0.57) | ADRB2SLC2A1KDM4ETP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303466-A2 | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-02-15 | — | — | EP | claimed |
| US-4990664-A | Drug for asthma or chronic bronchitis | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |
| EP-0303466-A2 | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-02-15 | — | — | EP | disclosed |