Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637934 | 0.79 | CYP2D6 (0.51) | TSHRCYP1A2CYP2D6CYP2C19MAPK1 | |
| SCHEMBL8629689 | 0.76 | TSHR (0.50) | TSHRCYP1A2CYP2D6CYP2C19MAPK1 | |
| Ammonia Solution, Strong SCHEMBL5810836 | 0.75 | CYP2D6 (0.51) | TSHRCYP1A2CYP2D6CYP2C19MAPK1 | |
| SCHEMBL1389524 | 0.74 | TDP1 (0.62) | TSHRCYP1A2CYP2D6CYP2C19MAPK1 | |
| SCHEMBL27934548 | 0.72 | TDP1 (0.55) | TSHRCYP1A2CYP2D6CYP2C19MAPK1 | |
| Acetic Acid SCHEMBL10786306 | 0.72 | TDP1 (0.55) | TSHRCYP1A2CYP2D6CYP2C19MAPK1 | |
| SCHEMBL5843591 | 0.72 | TDP1 (0.55) | TSHRCYP1A2CYP2D6CYP2C19MAPK1 | |
| Hydrazine SCHEMBL10799085 | 0.72 | TSHR (0.60) | TSHRCYP1A2CYP2D6CYP2C19MAPK1 | |
| SCHEMBL19046555 | 0.71 | CYP2D6 (0.59) | TSHRCYP1A2CYP2D6CYP2C19MAPK1 | |
| SCHEMBL17799037 | 0.71 | CYP2D6 (0.55) | TSHRCYP1A2CYP2D6CYP2C19MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045222-A | Liquid detergent formulations | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | claimed |
| US-5045222-A | Liquid detergent formulations | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |