Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RARB | P10826 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761850 | 1.00 | MAPT (0.53) | MAPTSMN1; SMN2RARBMEN1ALDH1A1 | |
| SCHEMBL9762384 | 1.00 | MAPT (0.53) | MAPTSMN1; SMN2RARBMEN1ALDH1A1 | |
| SCHEMBL9760791 | 1.00 | MAPT (0.53) | MAPTSMN1; SMN2RARBMEN1ALDH1A1 | |
| SCHEMBL9761074 | 0.96 | MAPT (0.57) | MAPTSMN1; SMN2RARBMEN1ALDH1A1 | |
| SCHEMBL9761544 | 0.96 | MAPT (0.50) | MAPTSMN1; SMN2RARBKMT2ATHRB | |
| SCHEMBL9761028 | 0.96 | MAPT (0.50) | MAPTSMN1; SMN2RARBKMT2ATHRB | |
| SCHEMBL9760351 | 0.95 | MAPT (0.56) | MAPTSMN1; SMN2RARBMEN1ALDH1A1 | |
| SCHEMBL9761109 | 0.95 | MAPT (0.56) | MAPTSMN1; SMN2RARBMEN1ALDH1A1 | |
| SCHEMBL9762036 | 0.95 | MAPT (0.56) | MAPTSMN1; SMN2RARBMEN1ALDH1A1 | |
| SCHEMBL9760282 | 0.95 | MAPT (0.56) | MAPTSMN1; SMN2RARBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297745-B1 | OPTICALLY ACTIVE ETHER DERIVATIVES, PREPARATION PROCESSES THEREFOR, LIQUID CRYSTAL MATERIALS AND AN OPTICAL SWITCHING ELEMENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-5013479-A | Aromatic ether esters containing two or three benzene rings | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-07 | — | — | US | disclosed |
| EP-0297745-A1 | Optically active ether derivatives, preparation processes therefor, liquid crystal materials and an optical switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-01-04 | — | — | EP | disclosed |