Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.90 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.90 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.76 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761663 | 1.00 | ADORA2A (0.90) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL10585648 | 0.97 | ADORA2A (0.88) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL10585629 | 0.97 | ADORA2A (0.88) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL9763035 | 0.97 | ADORA2A (0.87) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL9763054 | 0.97 | ADORA2A (0.87) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL5334414 | 0.95 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL5334412 | 0.95 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL9762476 | 0.94 | ADORA2A (0.98) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL9762486 | 0.94 | ADORA2A (0.98) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL9762338 | 0.89 | ADORA2A (0.83) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034381-A | Antagonist | CIBA-GEIGY CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |
| EP-0323807-A2 | Certain 2-substituted adenosine derivatives | CIBA-GEIGY AG (CH) | 1989-07-12 | — | — | EP | disclosed |