Clorophene

Clorophene

SCHEMBL9761818

Oc1ccc(Cl)cc1Cc1ccccc1.Oc1ccc(O)c(Cl)c1

nearest known ligand 0.79

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.79
KMT2A Q03164 3/20 0.79
HIF1A Q16665 3/20 0.79
CYP3A4 P08684 3/20 0.79
HSD17B10 Q99714 3/20 0.79
HPGD P15428 2/20 0.79
ALOX15 P16050 2/20 0.79
MAPT P10636 2/20 0.56
SLC22A1 O15245 1/20 0.56
USP2 O75604 1/20 0.56
LMNA P02545 1/20 0.56
HSP90AA1 P07900 1/20 0.56
HSPD1 P10809 1/20 0.56
HSPA5 P11021 1/20 0.56
IDO1 P14902 1/20 0.56
ALOX12 P18054 1/20 0.56
CASP1 P29466 1/20 0.56
HTT P42858 1/20 0.56
BLM P54132 1/20 0.56
HSPE1 P61604 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Clorophene SCHEMBL78119 0.89 HIF1A (1.00) MEN1KMT2AHIF1ACYP3A4HSD17B10
Clorophene SCHEMBL29377427 0.89 HIF1A (1.00) MEN1KMT2AHIF1ACYP3A4HSD17B10
Clorophene SCHEMBL7465363 0.88 HIF1A (0.84) MEN1KMT2AHIF1ACYP3A4HSD17B10
Clorophene SCHEMBL2811942 0.87 HIF1A (0.96) MEN1KMT2AHIF1ACYP3A4HSD17B10
Clorophene SCHEMBL29827182 0.87 HIF1A (0.96) MEN1KMT2AHIF1ACYP3A4HSD17B10
Clorophene SCHEMBL5160758 0.87 HIF1A (0.96) MEN1KMT2AHIF1ACYP3A4HSD17B10
Clorophene SCHEMBL2806718 0.87 HIF1A (0.96) MEN1KMT2AHIF1ACYP3A4HSD17B10
Dichlorophen SCHEMBL7043835 0.87 HIF1A (0.96) MEN1KMT2AHIF1ACYP3A4HSD17B10
Clorophene SCHEMBL30741300 0.87 HIF1A (0.96) MEN1KMT2AHIF1ACYP3A4HSD17B10
Clorophene SCHEMBL28120599 0.87 HIF1A (0.96) MEN1KMT2AHIF1ACYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273695-B1 METHOD OF PRODUCTION OF CATALYST CARRIER FOR POLYMERIZATION OF OLEFIN Tonen Corporation (JP) 1991-11-13 EP disclosed
EP-0273695-A1 Method of production of catalyst carrier for polymerization of olefin Tonen Corporation (JP) 1988-07-06 EP disclosed