Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344705 | 1.00 | TSHR (0.42) | TSHRTHRBSIRT2DNM1OPRM1 | |
| SCHEMBL5349789 | 1.00 | TSHR (0.42) | TSHRTHRBSIRT2DNM1OPRM1 | |
| SCHEMBL9763110 | 1.00 | TSHR (0.42) | TSHRTHRBSIRT2DNM1OPRM1 | |
| SCHEMBL5339781 | 1.00 | TSHR (0.42) | TSHRTHRBSIRT2DNM1OPRM1 | |
| SCHEMBL2429379 | 1.00 | TSHR (0.42) | TSHRTHRBSIRT2DNM1OPRM1 | |
| SCHEMBL5340532 | 1.00 | TSHR (0.42) | TSHRTHRBSIRT2DNM1OPRM1 | |
| SCHEMBL9763148 | 1.00 | TSHR (0.42) | TSHRTHRBSIRT2DNM1OPRM1 | |
| SCHEMBL5337289 | 1.00 | TSHR (0.42) | TSHRTHRBSIRT2DNM1OPRM1 | |
| SCHEMBL28463335 | 0.95 | TSHR (0.42) | TSHRTHRBSIRT2DNM1OPRM1 | |
| SCHEMBL27932076 | 0.80 | TSHR (0.33) | TSHRTHRBSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282579-B1 | CYCLOPENTANES AND LUBRICANTS COMPRISING CYCLOPENTANES | PENNZOIL PRODUCTS COMPANY (US) | 1991-11-27 | — | — | EP | claimed |