Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | OXTR | P30559 | 2/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8754394 | 0.83 | ESR2 (0.41) | ESR2OXTRAVPR1APTPN5CNR2 | |
| SCHEMBL4820116 | 0.83 | ESR2 (0.41) | ESR2OXTRAVPR1APTPN5CNR2 | |
| SCHEMBL4578608 | 0.82 | GRM2 (0.42) | ESR2OXTRAVPR1APTPN5CNR2 | |
| SCHEMBL4578614 | 0.82 | GRM2 (0.42) | ESR2OXTRAVPR1APTPN5CNR2 | |
| SCHEMBL9458241 | 0.82 | HRH3 (0.39) | ESR2 | |
| SCHEMBL9458247 | 0.82 | HRH3 (0.39) | ESR2 | |
| SCHEMBL10772663 | 0.81 | NPC1 (0.45) | ESR2CHRM3CHRM2CHRM1CYP3A4 | |
| SCHEMBL9344750 | 0.80 | ESR2 (0.39) | ESR2CHRM3CHRM2CHRM1CYP3A4 | |
| SCHEMBL9055349 | 0.80 | ESR2 (0.39) | ESR2CHRM3CHRM2CHRM1CYP3A4 | |
| SCHEMBL10514871 | 0.76 | ESR2 (0.38) | ESR2CHRM3CHRM2CHRM1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260450-B1 | LIQUID CRYSTAL DISPLAY | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-04 | — | — | EP | disclosed |