Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.55 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313345 | 1.00 | SPHK1 (0.55) | SPHK1SPHK2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL9313365 | 1.00 | SPHK1 (0.55) | SPHK1SPHK2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL9313336 | 1.00 | SPHK1 (0.55) | SPHK1SPHK2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL9763123 | 1.00 | SPHK1 (0.55) | SPHK1SPHK2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL9313357 | 1.00 | SPHK1 (0.55) | SPHK1SPHK2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL9314655 | 1.00 | SPHK1 (0.55) | SPHK1SPHK2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL9762739 | 1.00 | SPHK1 (0.55) | SPHK1SPHK2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL9314047 | 1.00 | SPHK1 (0.55) | SPHK1SPHK2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL9314646 | 1.00 | SPHK1 (0.55) | SPHK1SPHK2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL9763120 | 1.00 | SPHK1 (0.55) | SPHK1SPHK2CYP2C9CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425622-A1 | MESOGENIC COMPOUNDS. | MERCK PATENT GMBH (DE) | 1991-05-08 | — | — | EP | disclosed |