Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464040 | 0.99 | HRH3 (0.48) | HRH3SLC6A2HRH1KCNH2CHRM2 | |
| SCHEMBL9762919 | 0.85 | HRH3 (0.46) | HRH3SLC6A2HRH1KCNH2CHRM2 | |
| SCHEMBL10463990 | 0.84 | HRH3 (0.48) | HRH3SLC6A2HRH1KCNH2CHRM2 | |
| SCHEMBL10465456 | 0.84 | HRH3 (0.47) | HRH3SLC6A2HRH1KCNH2CHRM2 | |
| SCHEMBL10462962 | 0.81 | FFAR4 (0.46) | HRH3SLC6A2HRH1KCNH2CHRM2 | |
| SCHEMBL4809382 | 0.77 | CHKA (0.51) | HRH3L3MBTL3L3MBTL1BCHEACHE | |
| SCHEMBL12676672 | 0.76 | CHKA (0.53) | HRH3L3MBTL3L3MBTL1BCHEACHE | |
| SCHEMBL9763675 | 0.75 | HRH3 (0.41) | HRH3KCNH2HTR2CSIGMAR1 | |
| SCHEMBL20317448 | 0.74 | MEN1 (0.45) | L3MBTL1 | |
| SCHEMBL9763307 | 0.74 | MAOB (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |