Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17529670 | 0.79 | TSHR (0.38) | SMN1; SMN2HPGDKMT2ATSHRACHE | |
| SCHEMBL7715002 | 0.79 | TSHR (0.38) | SMN1; SMN2HPGDKMT2ATSHRACHE | |
| SCHEMBL11216483 | 0.78 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDKMT2ATSHRACHE | |
| SCHEMBL9762832 | 0.77 | TSHR (0.39) | HPGDTSHRACHE | |
| SCHEMBL780291 | 0.76 | KCNA5 (0.37) | SMN1; SMN2KMT2ATSHRACHELMNA | |
| SCHEMBL9016361 | 0.74 | TSHR (0.33) | SMN1; SMN2HPGDKMT2ATSHRACHE | |
| SCHEMBL11316444 | 0.72 | HTT (0.44) | LMNAGAA | |
| SCHEMBL28443365 | 0.72 | TSHR (0.40) | HPGDTSHRTP53 | |
| SCHEMBL1188529 | 0.71 | TSHR (0.47) | HPGDTSHRACHENPC1RAB9A | |
| SCHEMBL17529823 | 0.71 | POLB (0.37) | SMN1; SMN2HPGDKMT2ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068425-A | Nervous system disorders, intermediates for drugs and as enantiomorphs | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1991-11-26 | — | — | US | disclosed |
| US-4983768-A | Reacting an organic halide and an oxazaphospholidine in the absence of air, humidity and light | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1991-01-08 | — | — | US | disclosed |