Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | APEX1 | P27695 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | RECQL | P46063 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845694 | 0.95 | TDP1 (0.67) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9845689 | 0.93 | TDP1 (0.65) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL10693678 | 0.93 | TDP1 (0.71) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL8988471 | 0.93 | TDP1 (0.71) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9845579 | 0.93 | TDP1 (0.71) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9845589 | 0.92 | TDP1 (0.64) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL8177096 | 0.92 | TDP1 (0.69) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9845708 | 0.92 | TDP1 (0.63) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9845690 | 0.91 | TDP1 (0.62) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9813320 | 0.91 | TDP1 (0.69) | TDP1MAPTAPEX1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416814-A2 | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates | BEECHAM GROUP PLC (GB) | 1991-03-13 | — | — | EP | claimed |
| JP-3118381-A | — | — | None | — | — | JP | disclosed |
| JP-H03118381-A | NEW COMPOUND, ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | BEECHAM GROUP PLC | 1991-05-20 | — | — | JP | disclosed |
| EP-0416814-A2 | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates | BEECHAM GROUP PLC (GB) | 1991-03-13 | — | — | EP | disclosed |