Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588368 | 1.00 | ADORA2A (1.00) | ADORA2AADORA2BKDM4EALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL9762842 | 0.99 | ADORA2A (0.98) | ADORA2AADORA2BKDM4EALOX15HSD17B10 | |
| SCHEMBL9762726 | 0.93 | ADORA2A (0.87) | ADORA2AADORA2B | |
| Hydrochloric Acid SCHEMBL10587217 | 0.92 | ADORA2A (0.86) | ADORA2AADORA2B | |
| SCHEMBL9762938 | 0.92 | ADORA2A (0.84) | ADORA2AADORA2BADORA1 | |
| SCHEMBL9762920 | 0.92 | ADORA2A (0.84) | ADORA2AADORA2BADORA1 | |
| SCHEMBL10587027 | 0.90 | ADORA2A (0.82) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL10588074 | 0.90 | ADORA2A (0.82) | ADORA2AADORA2B | |
| SCHEMBL8373469 | 0.90 | ADORA2A (0.82) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL9762946 | 0.90 | ADORA2A (0.82) | ADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034381-A | Antagonist | CIBA-GEIGY CORPORATION (US) | 1991-07-23 | — | — | US | claimed |