Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.51 |
| ▸ | PPARG | P37231 | 17/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27388584 | 0.98 | PPARA (0.50) | PPARAPPARGCYP1A2GAACYP2C9 | |
| SCHEMBL11322441 | 0.87 | CYP1A2 (0.53) | PPARAPPARGCYP1A2GAACYP2C9 | |
| SCHEMBL1933913 | 0.87 | CYP1A2 (0.53) | PPARAPPARGCYP1A2GAACYP2C9 | |
| SCHEMBL1832086 | 0.86 | PPARA (0.63) | PPARAPPARG | |
| SCHEMBL2167153 | 0.85 | CYP1A2 (0.52) | PPARAPPARGCYP1A2GAACYP2C9 | |
| SCHEMBL1974348 | 0.84 | PPARG (0.54) | PPARAPPARGCYP1A2GAACYP2C9 | |
| SCHEMBL11587416 | 0.84 | PPARG (0.41) | PPARAPPARGCYP1A2GAACYP2C9 | |
| SCHEMBL4322251 | 0.84 | PPARG (0.54) | PPARAPPARGCYP1A2GAACYP2C9 | |
| SCHEMBL2952466 | 0.84 | PPARG (0.54) | PPARAPPARGCYP1A2GAACYP2C9 | |
| Water SCHEMBL9256164 | 0.82 | PPARG (0.53) | PPARAPPARGCYP1A2GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021439-A | Senile dementia and memory dysfunction | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0367393-A2 | New heterocyclic compounds, production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-05-09 | — | — | EP | disclosed |