Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763680 | 0.89 | TDP1 (0.42) | TDP1L3MBTL1MEN1KMT2AFFAR1 | |
| SCHEMBL10488184 | 0.84 | TDP1 (0.47) | TDP1L3MBTL1MEN1KMT2AFFAR1 | |
| SCHEMBL6001883 | 0.83 | TDP1 (0.52) | TDP1L3MBTL1MEN1KMT2AFFAR1 | |
| SCHEMBL97038 | 0.83 | TDP1 (0.52) | TDP1L3MBTL1MEN1KMT2AFFAR1 | |
| SCHEMBL2010505 | 0.83 | TDP1 (0.52) | TDP1L3MBTL1MEN1KMT2AFFAR1 | |
| SCHEMBL9407052 | 0.81 | TDP1 (0.53) | TDP1L3MBTL1MEN1KMT2AFFAR1 | |
| SCHEMBL97369 | 0.81 | TDP1 (0.53) | TDP1L3MBTL1MEN1KMT2AFFAR1 | |
| SCHEMBL8553636 | 0.81 | TDP1 (0.53) | TDP1L3MBTL1MEN1KMT2AFFAR1 | |
| SCHEMBL9574223 | 0.81 | TDP1 (0.53) | TDP1L3MBTL1MEN1KMT2AFFAR1 | |
| SCHEMBL96692 | 0.81 | TDP1 (0.53) | TDP1L3MBTL1MEN1KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |
| US-4853382-A | TREATING ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0178919-B1 | AMINOPHENOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4730008-A | STIMULANT FOR BETA-ADRENORECEPTORS | GLAXO GROUP LIMITED (GB) | 1988-03-08 | — | — | US | disclosed |
| EP-0178919-A2 | Aminophenol derivatives | GLAXO GROUP LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |